Infusion and transfusion therapy: main aspects

Post-transfusion purpura: immunologic aspects and therapy.

Perinatal Transfusion Medicine – Immunological Aspects

The concept of compatibility is dependent on the specifity of immune responses. The immunology of reproduction, and in particular the tolerance of two genetically distinct organisms and their fruitful symbiosis, is one of the most imposing paradoxes in immunology. In normal human pregnancy, the allogeneic embryo is tolerated by the maternal immune system for about 40 weeks without general immun...

Transfusion Iron Chelation Therapy

As a unique electron donor and acceptor, iron is an essential element in most biological systems. However, its chemical reactivity can result in iron potentially becoming a toxin when present in excessive quantities; accordingly, total body iron must be tightly regulated. As humans have no physiological mechanism for the elimination of excess iron, body iron is controlled mainly by the degree o...

Regulating transfusion therapy.

Several recent events are worthy of no­ tice by the practicing physician since they affect blood bank services to his patient. The Food and Drug Administration has announced that it has extended Federal regulation from interstate'on to intrastate blood banking. As a first step, all blood banks, including hospital blood banks, must register.* The action can mean a new set of standards and rules ...

Massive blood transfusion therapy.

Surgical patients requiring massive blood transfusion therapy present many challenges for the anesthetist. The decision to transfuse homologous banked blood and its components must be weighed against the potential complications that may occur in this form of therapy. A review of metabolic changes that occur in banked blood, the risk of infection, and physiologic derangements that may develop du...